Human FAF2/ FAS-associated factor 2 CLIA Kit
FAS相关因子2

货号:

U6959h

商标:

EIAab^®

监管等级:

RUO

别名:

Protein ETEA, UBX domain-containing protein 3B, UBX domain-containing protein 8, ETEA, KIAA0887, UBXD8, UBXN3B

检测方法:

CLIA

特异性:

Natural and recombinant human FAS-associated factor 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human FAF2 CLIA Kit

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通用注释

亚单元:

Identified in a complex that contains SEL1L, OS9, FAF2/UBXD8, UBE2J1/UBC6E and AUP1 (PubMed:18711132). Interacts with YOD1 (PubMed:19818707). Interacts (via N-terminus) with UBQLN2 (via C-terminus) (PubMed:24215460). Interacts with PNPLA2 and UBAC2 (PubMed:23297223).

功能:

Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223).

亚细胞位置:

Cytoplasm Lipid droplet Endoplasmic reticulum

数据库链接

UniGene:

Hs.484242

SMR:

Q96CS3

STRING:

9606.ENSP00000261942

KEGG:

hsa:23197

MIM: