Human FBLN1/ Fibulin-1 CLIA Kit
衰老关键蛋白1

货号:

U0136h

商标:

EIAab^®

监管等级:

RUO

别名:

PP213, FIBL-1

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

62.5-4000pg/mL

特异性:

Natural and recombinant human Fibulin-1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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Human FBLN1 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献 ( 1 )
序列 / 3D
反馈墙 (0)

通用注释

亚单元:

Homomultimerizes and interacts with various extracellular matrix components such as FN1, LAMA1, LAMA2, NID, ACAN, CSPG2 and type IV collagen. Interacts also with APP, NOV, FGB and HPV type 16, HPV type 18, HPV type 31 and BPV type 1 E6 proteins. Interacts with FBLN7.

功能:

Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.

亚细胞位置:

Secreted Extracellular space Extracellular matrix

数据库链接

UniGene:

Hs.24601

STRING:

9606.ENSP00000331544

KEGG:

hsa:2192

MIM:

135820

Pfam: