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FCER1G (基因名), High affinity immunoglobulin epsilon receptor subunit gamma (蛋白名), fcerg_pig.

产品名称:

Pig FCER1G/ High affinity immunoglobulin epsilon receptor subunit gamma CLIA Kit

货号:

U5870p

商标:

EIAab^®

监管等级:

RUO

别名:

Fc receptor gamma-chain, Fc-epsilon RI-gamma, IgE Fc receptor subunit gamma, FcRgamma, FceRI gamma

检测方法:

CLIA

特异性:

Natural and recombinant pig High affinity immunoglobulin epsilon receptor subunit gamma

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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产品说明书

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通用注释

亚单元:

IgE Fc receptor is a tetramer of an alpha chain, a beta chain, and two disulfide linked gamma chains. The gamma chain from Fc-epsilon-Ri are also subunits of other Fc receptors like FCGR1A (By similarity). Associated with CLEC6A (By similarity). Interacts with CLEC4E (By similarity). Interacts (via ITAM domain) with SYK (via SH2 domains); activates SYK, enabling integrin-mediated activation of neutrophils and macrophages (By similarity). Interacts with CD300LH; the interaction may be indirect (By similarity). Interacts with CD300LD.

功能:

Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin.

亚细胞位置:

Cell membrane Single-pass type I membrane protein

数据库链接

UniGene:

Ssc.71807

SMR:

Q9XSZ6

STRING:

9823.ENSSSCP00000006776

KEGG:

ssc:397406

Pfam: