FNTA (基因名), Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (蛋白名), fnta_human.
产品名称:
Human FNTA/ Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha CLIA Kit
货号:
U12643h
商标:
EIAab®
监管等级:
别名:
CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha
检测方法:
CLIA
特异性:
Natural and recombinant human Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with MUSK; the interaction is direct and mediates AGRIN-induced phosphorylation of FNTA (By similarity). Heterodimer of FNTA and FNTB (farnesyltransferase). Heterodimer of FNTA and PGGT1B (geranylgeranyltransferase).
功能:
Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
亚细胞位置:
N/A
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