Human FOPNL/ LisH domain-containing protein FOPNL CLIA Kit
含结构域蛋白FOPNL

货号:

U2071h

商标:

EIAab^®

监管等级:

RUO

别名:

FGFR1OP N-terminal-like protein, FOP-related protein of 20 kDa, C16orf63, FOR20, PHSECRG2

检测方法:

CLIA

特异性:

Natural and recombinant human LisH domain-containing protein FOPNL

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human FOPNL CLIA Kit

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通用注释

亚单元:

Homooligomer; probably required for localization to centrosomes (PubMed:20551181). Forms a complex with KIAA0753/OFIP and OFD1; within this complex may stabilize the interaction between OFD1 and KIAA0753/OFIP (PubMed:26643951). Interacts with PCM1; this interaction may be mediated by KIAA0753/OFIP (PubMed:26643951). Interacts with PLK1 in later G1, S, G2 and M phases of the cell cycle; this interaction recruits PLK1 to centrosomes (PubMed:24018379).

功能:

Involved in the biogenesis of cilia (PubMed:20551181). Required for the recruitement of PLK1 to centrosomes and S phase progression (PubMed:24018379).

亚细胞位置:

Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Centriole Cell projection Cilium Cytoplasm Cytoskeleton Cilium basal body Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Cytoplasmic granule Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Centriolar satellite Localizes to the centrosome throughout cell cycle progression (PubMed:24018379). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (PubMed:26643951).

数据库链接

UniGene:

Hs.514179

SMR:

Q96NB1

STRING:

9606.ENSP00000255759

KEGG:

hsa:123811

MIM:

617149

Pfam: