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Hat1 (基因名), Histone acetyltransferase type B catalytic subunit (蛋白名), hat1_mouse.

产品名称:

Mouse Hat1/ Histone acetyltransferase type B catalytic subunit CLIA Kit
组蛋白乙酰转移酶B型催化亚单位

货号:

U15268m

商标:

EIAab^®

监管等级:

RUO

别名:

Histone acetyltransferase 1

检测方法:

CLIA

特异性:

Natural and recombinant mouse Histone acetyltransferase type B catalytic subunit

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Development Biology

规格 & 价格:

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通用注释

亚单元:

Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A. The interaction is dependent of the ability of RBBP7 to bind to the N-terminus of histones. Component of the histone H3.1 and H3.3 complexes.

功能:

Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes.

亚细胞位置:

Nucleus matrix

数据库链接

UniGene:

Mm.272472

SMR:

Q8BY71

STRING:

10090.ENSMUSP00000028408

KEGG:

mmu:107435

Pfam: