HBEGF (基因名), Proheparin-binding EGF-like growth factor (蛋白名), hbegf_human.
产品名称:
Human HBEGF/ Proheparin-binding EGF-like growth factor CLIA Kit
肝素结合性表皮生长因子
货号:
U1479h
商标:
EIAab®
监管等级:
别名:
DTR, DTS, HEGFL
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
3.9-250pg/mL
特异性:
Natural and recombinant human Proheparin-binding EGF-like growth factor
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with FBLN1 (By similarity). Interacts with EGFR and ERBB4.
功能:
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
亚细胞位置:
Proheparin-binding EGF-like growth factor
Cell membrane
Single-pass type I membrane protein
数据库链接
验证序列:
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