IL15RA (基因名), Interleukin-15 receptor subunit alpha (蛋白名), i15ra_human.
产品名称:
Human IL15RA/ Interleukin-15 receptor subunit alpha CLIA Kit
白细胞介素-15受体亚单位
货号:
U1035h
商标:
EIAab®
监管等级:
别名:
CD215, IL-15 receptor subunit alpha
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
7.8-500pg/mL
特异性:
Natural and recombinant human Interleukin-15 receptor subunit alpha
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
The interleukin-15 receptor IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL15RA also self-associates (By similarity). Interacts with SYK.
功能:
High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves SYK.
亚细胞位置:
Soluble interleukin-15 receptor subunit alpha
Secreted
Extracellular space
[1].
D. Valadés, J. Bujan, C.V Martínez, et al.
[2].
A Pérez-López, P Gonzalo-Encabo, B Pérez-Köhler, et al.
[4].
J.McKendry, M.Martin-Rincon, D.Morales-Alamo, et al.
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