IGF1 (基因名), Insulin-like growth factor I (蛋白名), igf1_chick.
产品名称:
Chicken IGF1/ Insulin-like growth factor I CLIA Kit
胰岛素样生长因子1
货号:
U0050c
商标:
EIAab®
监管等级:
别名:
Somatomedin, IGF-I
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
10.9-700pg/mL
特异性:
Natural and recombinant chicken Insulin-like growth factor I
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Metabolism
通用注释
亚单元:
N/A
功能:
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.
亚细胞位置:
Secreted
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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