Human IL1R2/ Interleukin-1 receptor type 2 CLIA Kit
白介素1可溶性受体Ⅱ

货号:

U0066h

商标:

EIAab^®

监管等级:

RUO

别名:

CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, Interleukin-1 receptor type II, IL-1R-beta, CD121b, IL-1R-2, IL1RB

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

3.9-250pg/mL

特异性:

Natural and recombinant human Interleukin-1 receptor type 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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Human IL1R2 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
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通用注释

亚单元:

Associates with IL1RAP to form a non-signaling interleukin-1 receptor complex.

功能:

Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

亚细胞位置:

Isoform Long Cell membrane Single-pass type I membrane protein

数据库链接

UniGene:

Hs.25333

SMR:

P27930

STRING:

9606.ENSP00000330959

KEGG:

hsa:7850

MIM: