INVS (基因名), Inversin (蛋白名), invs_chick.
通用注释
亚单元:
Binds calmodulin via its IQ domains. Interacts with APC2.
功能:
Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling.
亚细胞位置:
Cytoplasm
Cytoplasm
Cytoskeleton
Associates with the cytoskeleton.
数据库链接
该产品尚未在任何出版物中被引用。
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