ACOD1 (基因名), Cis-aconitate decarboxylase (蛋白名), irg1_human.
产品名称:
Human ACOD1/ Cis-aconitate decarboxylase CLIA Kit
货号:
U15800h
商标:
EIAab®
监管等级:
别名:
Aconitate decarboxylase, Aconitate decarboxylase 1, Cis-aconitic acid decarboxylase, Immune-responsive gene 1 protein, CAD, IRG1
检测方法:
CLIA
特异性:
Natural and recombinant human Cis-aconitate decarboxylase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
亚细胞位置:
Mitochondrion
数据库链接
UniGene:
SMR:
STRING:
KEGG:
MIM:
Pfam:
Uniprot:
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