Jag1 (基因名), Protein jagged-1 (蛋白名), jag1_rat.
通用注释
亚单元:
Interacts with NOTCH1, NOTCH2 and NOTCH3.
功能:
Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. May regulate fibroblast growth factor-induced angiogenesis.
亚细胞位置:
Membrane
Single-pass type I membrane protein
数据库链接
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