Rat Jtb/ Protein JTB CLIA Kit

货号:

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

特异性:

Natural and recombinant rat Protein JTB

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

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Rat Jtb CLIA Kit

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通用注释

亚单元:

Interacts with AURKA, AURKB, BIRC5 and INCENP. May be a component of the CPC at least composed of BIRC5/survivin, CDCA8/borealin, INCENP and AURKB/Aurora-B.

功能:

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.

亚细胞位置:

Membrane Single-pass type I membrane protein Mitochondrion Cytoplasm Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Cytoplasm Cytoskeleton Spindle Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase (By similarity).

数据库链接

UniGene:

Rn.91803

SMR:

O88823

STRING:

10116.ENSRNOP00000060227

KEGG:

rno:29439

Pfam:

PF05439

Uniprot: