KAZN (基因名), Kazrin (蛋白名), kazrn_human.
通用注释
亚单元:
Isoform 2, isoform 3 and isoform 4 interact with PPL N-terminus.
功能:
Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
亚细胞位置:
Isoform 4
Cytoplasm
Cell junction
Desmosome
Nucleus
Observed at the apical plasma membrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.
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