Kcnc1 (基因名), Potassium voltage-gated channel subfamily C member 1 (蛋白名), kcnc1_rat.
产品名称:
Rat Kcnc1/ Potassium voltage-gated channel subfamily C member 1 CLIA Kit
货号:
U2326r
商标:
EIAab®
监管等级:
别名:
NGK2, RAW2, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4
检测方法:
CLIA
特异性:
Natural and recombinant rat Potassium voltage-gated channel subfamily C member 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Heteromultimer with KCNG3, KCNG4 and KCNV2 (By similarity). Heteromultimer with KCNC2 (PubMed:10482766, PubMed:14679187). Heterotetramer with KCNC3 (By similarity). Interacts with the ancillary subunits KCNE1 and KCNE2; the interaction modulates channel activity (PubMed:14679187).
功能:
Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient (PubMed:10482766, PubMed:14679187). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well (PubMed:10482766, PubMed:14679187). Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons (PubMed:10482766).
亚细胞位置:
Cell membrane
Multi-pass membrane protein
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