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KCNQ2 (基因名), Potassium voltage-gated channel subfamily KQT member 2 (蛋白名), kcnq2_human.

产品名称:

Human KCNQ2/ Potassium voltage-gated channel subfamily KQT member 2 CLIA Kit
钾电压门控通道亚家族KQT成员2

货号:

U2348h

商标:

EIAab^®

监管等级:

RUO

别名:

KQT-like 2, Neuroblastoma-specific potassium channel subunit alpha KvLQT2, Voltage-gated potassium channel subunit Kv7.2

检测方法:

CLIA

特异性:

Natural and recombinant human Potassium voltage-gated channel subfamily KQT member 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Neurosciences

规格 & 价格:

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通用注释

亚单元:

Heteromultimer with KCNQ3. May associate with KCNE2.

功能:

Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. KCNQ2/KCNQ3 current is blocked by linopirdine and XE991, and activated by the anticonvulsant retigabine. Muscarinic agonist oxotremorine-M strongly suppress KCNQ2/KCNQ3 current in cells in which cloned KCNQ2/KCNQ3 channels were coexpressed with M1 muscarinic receptors.

亚细胞位置:

Membrane Multi-pass membrane protein

数据库链接

UniGene:

Hs.161851

STRING:

9606.ENSP00000352035

KEGG:

hsa:3785

MIM:

121200

Pfam: