LAMP2 (基因名), Lysosome-associated membrane glycoprotein 2 (蛋白名), lamp2_human.
产品名称:
Human LAMP2/ Lysosome-associated membrane glycoprotein 2 CLIA Kit
溶酶体相关膜糖蛋白2
货号:
U1464h
商标:
EIAab®
监管等级:
别名:
CD107 antigen-like family member B, LGP-96, CD107b, LAMP-2
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
39-2500pg/mL
特异性:
Natural and recombinant human Lysosome-associated membrane glycoprotein 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cardiovascular
通用注释
亚单元:
Monomer (PubMed:18644871, PubMed:25342746). Homodimer (PubMed:25342746). Homotrimer (PubMed:25342746). Forms large homooligomers (PubMed:18644871). Interacts (via its cytoplasmic region) with HSPA8 (PubMed:25342746). Interacts with HSP90 in the lysosome lumen; this enhances LAMP2 stability (By similarity). Interacts with MLLT11 (PubMed:24880125).
功能:
Isoform LAMP-2C: Modulates chaperone-mediated autophagy. Decreases presentation of endogenous antigens by MHCII. Does not play a role in the presentation of exogenous and membrane-derived antigens by MHCII.
亚细胞位置:
Cell membrane
Single-pass type I membrane protein
Endosome membrane
Single-pass type I membrane protein
Lysosome membrane
Single-pass type I membrane protein
Cytoplasmic vesicle
Autophagosome membrane
This protein shuttles between lysosomes, endosomes, and the plasma membrane.
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