Human L1RE1/ LINE-1 retrotransposable element ORF1 protein CLIA Kit

货号:

U16026h

商标:

EIAab^®

监管等级:

RUO

别名:

LINE retrotransposable element 1, LINE1 retrotransposable element 1, L1ORF1p, LRE1

检测方法:

CLIA

特异性:

Natural and recombinant human LINE-1 retrotransposable element ORF1 protein

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human L1RE1 CLIA Kit

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通用注释

亚单元:

Homotrimer (via coiled coil domain). May also form larger homooligomers. May interact with DDX39A, HNRNPA1, SERBP1 and YBX1.

功能:

Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. May function as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.

亚细胞位置:

Cytoplasm Nucleus Nucleolus Colocalizes with cytoplasmic ribonucleoprotein particle (RNP) (PubMed:16183655). Identified with its own transcript in a cytoplasmic ribonucleoprotein complex (PubMed:16183655). Mainly cytoplasmic where it is enriched in stress granules but also more rarely detected in the nucleolus (PubMed:17562864).

数据库链接

SMR:

Q9UN81

MIM:

151626

Pfam:

PF02994

Uniprot:

Q9UN81

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