Map3k11 (基因名), Mitogen-activated protein kinase kinase kinase 11 (蛋白名), m3k11_mouse.
产品名称:
Mouse Map3k11/ Mitogen-activated protein kinase kinase kinase 11 CLIA Kit
丝裂原活化蛋白激酶激酶11
货号:
U10353m
商标:
EIAab®
监管等级:
别名:
Mixed lineage kinase 3, Mlk3
检测方法:
CLIA
特异性:
Natural and recombinant mouse Mitogen-activated protein kinase kinase kinase 11
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Homodimer; undergoes dimerization during activation. Interacts with MAP2K4/MKK4 and MAP2K7/MKK7.
功能:
Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
亚细胞位置:
Cytoplasm
Cytoskeleton
Microtubule organizing center
Centrosome
Location is cell cycle dependent.
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