MAP3K14 (基因名), Mitogen-activated protein kinase kinase kinase 14 (蛋白名), m3k14_human.
产品名称:
Human MAP3K14/ Mitogen-activated protein kinase kinase kinase 14 CLIA Kit
货号:
U10356h
商标:
EIAab®
监管等级:
别名:
NF-kappa-beta-inducing kinase, Serine/threonine-protein kinase NIK, HsNIK, NIK
检测方法:
CLIA
特异性:
Natural and recombinant human Mitogen-activated protein kinase kinase kinase 14
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Interacts with TRAF2, TRAF5, TRAF6, IKKA and NFKB2/P100 (By similarity). Interacts with TRAF3 and PELI3. Interacts with NIBP; the interaction is direct. Interacts with ARRB1 and ARRB2. Interacts with GRB10. Interacts with ZFP91.
功能:
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-kappa-B via the non-canonical pathway. Could act in a receptor-selective manner.
亚细胞位置:
Cytoplasm
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