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MAP3K20 (基因名), Mitogen-activated protein kinase kinase kinase 20 (蛋白名), m3k20_human.

产品名称:

Human MAP3K20/ Mitogen-activated protein kinase kinase kinase 20 CLIA Kit
丝裂原活化蛋白激酶激酶激酶MLT

货号:

U15205h

商标:

EIAab^®

监管等级:

RUO

别名:

Human cervical cancer suppressor gene 4 protein, Leucine zipper- and sterile alpha motif-containing kinase, MLK-like mitogen-activated protein triple kinase, Mitogen-activated protein kinase kinase kinase MLT, Mixed lineage kinase-related kinase, Sterile alpha motif- and leucine zipper-containing kinase AZK, HCCS-4, MLK-related kinase, HCCS4, MLTK, ZAK

检测方法:

CLIA

特异性:

Natural and recombinant human Mitogen-activated protein kinase kinase kinase 20

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Human MAP3K20 CLIA Kit

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产品说明书

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通用注释

亚单元:

Homodimer (PubMed:10924358, PubMed:26755636). Interacts with PKN1 and ZNF33A (PubMed:12535642, PubMed:12761180). Component of a signaling complex containing at least AKAP13, PKN1, MAPK14, MAP3K20 and MAP2K3. Within this complex, AKAP13 interacts directly with PKN1, which in turn recruits MAPK14, MAP2K3 and MAP3K20 (PubMed:21224381).

功能:

Isoform 1: Phosphorylates histone H3 at 'Ser-28' (PubMed:15684425). May have role in neoplastic cell transformation and cancer development (PubMed:15172994). Causes cell shrinkage and disruption of actin stress fibers (PubMed:11042189).

亚细胞位置:

Cytoplasm Nucleus Translocates to the nucleus upon ultraviolet B irradiation.

数据库链接

UniGene:

Hs.444451

SMR:

Q9NYL2

STRING:

9606.ENSP00000364361

KEGG:

hsa:51776

MIM: