MAL2 (基因名), Protein MAL2 (蛋白名), mal2_human.
通用注释
亚单元:
Interacts with TPD52L2.
功能:
Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway.
亚细胞位置:
Cell membrane
Multi-pass membrane protein
Apical cell membrane
Multi-pass membrane protein
Endomembrane system
Cytoplasm
Perinuclear region
Associated with lipid rafts. In polarized epithelial cells, restricted to the apical surface. In hepatocytes, as well as in polarized hepatoma Hep-G2 cells, found in the canalicular membrane, equivalent to the apical surface, beneath the canalicular actin cytoskeleton. In non-polarized Hep-G2 cells, distributed to the perinuclear region.
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