MBL2 (基因名), Mannose-binding protein C (蛋白名), mbl2_pig.
产品名称:
Pig MBL2/ Mannose-binding protein C CLIA Kit
甘露糖结合蛋白C
货号:
U1480p
商标:
EIAab®
监管等级:
别名:
27 kDa mannan-binding protein monomeric subunit, Mannose-binding lectin, pMBP-27, MBL, MBP-C
检测方法:
CLIA
特异性:
Natural and recombinant pig Mannose-binding protein C
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Immunology
通用注释
亚单元:
Interacts with MASP1 and MASP2. Interacts with MEP1A and MEP1B and may inhibit their catalytic activity (By similarity). Forms oligomeric complexes of 2 or 3 homotrimers.
功能:
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. According to some authors, it only binds mannose (PubMed:8602463).
亚细胞位置:
Secreted
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