Mouse Mif/ Macrophage migration inhibitory factor CLIA Kit
巨噬细胞迁移抑制因子

货号:

U0698m

商标:

EIAab^®

监管等级:

RUO

别名:

Delayed early response protein 6, Glycosylation-inhibiting factor, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase, DER6, GIF, MIF

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

7.8-500pg/mL

特异性:

Natural and recombinant mouse Macrophage migration inhibitory factor

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

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Mouse Mif CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献 ( 3 )
序列 / 3D
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通用注释

亚单元:

Homotrimer. Interacts with BNIPL (By similarity). Interacts with the CD74 extracellular domain. Interacts with COPS5 and with the CXCR2 extracellular domain.

功能:

Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

亚细胞位置:

Secreted Cytoplasm Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens (By similarity).

数据库链接

UniGene:

Mm.2326

SMR:

P34884

STRING:

10090.ENSMUSP00000041149

KEGG:

mmu:17319

Pfam:

PF01187

Uniprot: