Mapk4 (基因名), Mitogen-activated protein kinase 4 (蛋白名), mk04_mouse.
产品名称:
Mouse Mapk4/ Mitogen-activated protein kinase 4 CLIA Kit
货号:
U10347m
商标:
EIAab®
监管等级:
别名:
Extracellular signal-regulated kinase 4, ERK-4, MAP kinase 4, Erk4, Prkm4
检测方法:
CLIA
特异性:
Natural and recombinant mouse Mitogen-activated protein kinase 4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Homodimer. Heterodimer with ERK3/MAPK6. Interacts with (via FRIEDE motif) MAPKAPK5.
功能:
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.
亚细胞位置:
Cytoplasm
Nucleus
Translocates to the cytoplasm following interaction with MAPKAPK5.
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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