MAPK14 (基因名), Mitogen-activated protein kinase 14 (蛋白名), mk14_canfa.
产品名称:
Dog MAPK14/ Mitogen-activated protein kinase 14 CLIA Kit
促分裂原活化蛋白激酶14
货号:
U9114d
商标:
EIAab®
监管等级:
别名:
Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, MAP kinase 14, MAPK 14, CSBP1, CSBP2
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant dog Mitogen-activated protein kinase 14
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Binds to a kinase interaction motif within the protein tyrosine phosphatase, PTPRR. This interaction retains MAPK14 in the cytoplasm and prevents nuclear accumulation. Interacts with FAM48A, SPAG9 and NP60.
功能:
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO during hypoxic stress.
亚细胞位置:
Cytoplasm
Nucleus
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