Rat Mmp2/ 72 kDa type IV collagenase CLIA Kit
基质金属蛋白酶2/明胶酶A

货号:

U0100r

商标:

EIAab^®

监管等级:

RUO

别名:

72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant rat 72 kDa type IV collagenase

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

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Rat Mmp2 CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

数据
文献 ( 2 )
序列 / 3D
反馈墙 (0)

通用注释

亚单元:

Interacts (via the C-terminal hemopexin-like domains-containing region) with the integrin alpha-V/beta-3; the interaction promotes vascular invasion in angiogenic vessels and melamoma cells. Interacts (via the C-terminal PEX domain) with TIMP2 (via the C-terminal); the interaction inhibits the degradation activity. Interacts with GSK3B.

功能:

PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrin alpha-v/beta3 on the surface of blood vessels.

亚细胞位置:

Secreted Extracellular space Extracellular matrix Membrane Nucleus Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes (By similarity).

数据库链接

UniGene:

Rn.6422

SMR:

P33436

STRING:

10116.ENSRNOP00000022679

KEGG:

rno:81686

Pfam:

PF00040

Uniprot: