Map2k5 (基因名), Dual specificity mitogen-activated protein kinase kinase 5 (蛋白名), mp2k5_rat.
产品名称:
Rat Map2k5/ Dual specificity mitogen-activated protein kinase kinase 5 CLIA Kit
双特异性促分裂原活化蛋白激酶激酶5
货号:
U10343r
商标:
EIAab®
监管等级:
别名:
MAPK/ERK kinase 5, MEK 5, MAP kinase kinase 5, Mek5, Mkk5, Prkmk5
检测方法:
CLIA
特异性:
Natural and recombinant rat Dual specificity mitogen-activated protein kinase kinase 5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Interacts with PARD6A, MAP3K3 and MAPK7. Forms a complex with SQSTM1 and PRKCZ or PRKCI.
功能:
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
亚细胞位置:
Isoform Alpha-2
Membrane
The alternatively spliced exon in alpha isoform resemble conserved sequences that mediate interactions with the cytoskeleton, thereby explaining the differential localization.
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