Human MCAM/ Cell surface glycoprotein MUC18 CLIA Kit
细胞表面糖蛋白MUC18

货号:

U1670h

商标:

EIAab^®

监管等级:

RUO

别名:

Cell surface glycoprotein P1H12, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, CD146, MUC18

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

78-5000pg/mL

特异性:

Natural and recombinant human Cell surface glycoprotein MUC18

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human MCAM CLIA Kit

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产品说明书

说明书:

MSDS:

在线询价

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通用注释

亚单元:

N/A

功能:

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

亚细胞位置:

Membrane Single-pass type I membrane protein

数据库链接

UniGene:

Hs.599039

STRING:

9606.ENSP00000264036

KEGG:

hsa:4162

MIM:

155735

Pfam: