Rat Nfe2l2/ Nuclear factor erythroid 2-related factor 2 CLIA Kit
核因子NF-E2相关因子2

货号:

U3093r

商标:

EIAab^®

监管等级:

RUO

别名:

Nuclear factor, erythroid derived 2, like 2, NF-E2-related factor 2, Nrf2

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant rat Nuclear factor erythroid 2-related factor 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

规格 & 价格:

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Rat Nfe2l2 CLIA Kit

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产品说明书

说明书:

MSDS:

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通用注释

亚单元:

Heterodimer. Forms a ternary complex with PGAM5 and KEAP1. Interacts via its leucine-zipper domain with the coiled-coil domain of PMF1. Interacts with EEF1D at heat shock promoter elements (HSE). Interacts (via the bZIP domain) with MAFK; required for binding to antioxidant response (ARE) elements on DNA. Interacts with CHD6; involved in activation of the transcription.

功能:

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

亚细胞位置:

Cytoplasm Cytosol Nucleus Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.

数据库链接

UniGene:

Rn.10867

SMR:

O54968

STRING:

10116.ENSRNOP00000002114

KEGG:

rno:83619

Pfam: