OLFM4 (基因名), Olfactomedin-4 (蛋白名), olfm4_human.
产品名称:
Human OLFM4/ Olfactomedin-4 CLIA Kit
Olfactomedin-4
货号:
U8723h
商标:
EIAab®
监管等级:
别名:
Antiapoptotic protein GW112, G-CSF-stimulated clone 1 protein, hOLfD, hGC-1, UNQ362/PRO698, OLM4, GW112
检测方法:
CLIA
特异性:
Natural and recombinant human Olfactomedin-4
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Homomultimer; disulfide-linked. Interacts with NDUFA13. Interacts with cell surface lectins (locutions ricinus communis agglutinin I, concanavalin-A and wheat germ agglutinin) and cadherin.
功能:
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
亚细胞位置:
Secreted
Extracellular space
Mitochondrion
Subcellular location is not clearly defined: has been shown to be secreted (PubMed:16566923), but also in the mitochondrion (PubMed:15059901 and PubMed:20724538), cytoplasm and plasma membrane (PubMed:20724538) and in the nucleus (PubMed:15059901).
该产品尚未在任何出版物中被引用。
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