OPTN (基因名), Optineurin (蛋白名), optn_chick.
通用注释
亚单元:
Binds to linear ubiquitin chains. Interacts with LC3 family members.
功能:
Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis. May act as autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family.
亚细胞位置:
Cytoplasm
Golgi apparatus
Cytoplasmic vesicle
Autophagosome
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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