PAPPA (基因名), Pappalysin-1 (蛋白名), papp1_human.
产品名称:
Human PAPPA/ Pappalysin-1 CLIA Kit
冠毛素1
货号:
U0800h
商标:
EIAab®
监管等级:
别名:
Insulin-like growth factor-dependent IGF-binding protein 4 protease, Pregnancy-associated plasma protein A, IGF-dependent IGFBP-4 protease, PAPP-A
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
7.8-500pg/mL
特异性:
Natural and recombinant human Pappalysin-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Homodimer; disulfide-linked. In pregnancy serum, predominantly found as a disulfide-linked 2:2 heterotetramer with the proform of PRG2.
功能:
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
亚细胞位置:
Secreted
[1].
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