Human PDGFA/ Platelet-derived growth factor subunit A CLIA Kit
血小板源生长因子亚基A

货号:

U0112h

商标:

EIAab^®

监管等级:

RUO

别名:

PDGF-1, Platelet-derived growth factor A chain, Platelet-derived growth factor alpha polypeptide, PDGF subunit A, PDGF1

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

3.9-250pg/mL

特异性:

Natural and recombinant human Platelet-derived growth factor subunit A

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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产品说明书

说明书:

MSDS:

在线询价

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通用注释

亚单元:

Homodimer; antiparallel disulfide-linked dimer. Heterodimer with PDGFB; antiparallel disulfide-linked dimer. The PDGFA homodimer interacts with PDGFRA homodimers, and with heterodimers formed by PDGFRA and PDGFRB. The heterodimer composed of PDGFA and PDGFB interacts with PDGFRA homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts with CSPG4.

功能:

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB.

亚细胞位置:

Secreted Released by platelets upon wounding.

数据库链接

UniGene:

Hs.535898

SMR:

P04085

STRING:

9606.ENSP00000346508

KEGG:

hsa:5154

MIM: