Mouse Pdgfb/ Platelet-derived growth factor subunit B CLIA Kit
血小板衍生生长因子B

货号:

U0633m

商标:

EIAab^®

监管等级:

RUO

别名:

PDGF-2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Proto-oncogene c-Sis, PDGF subunit B, Sis

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

3.9-250pg/mL

特异性:

Natural and recombinant mouse Platelet-derived growth factor subunit B

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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产品说明书

说明书:

MSDS:

在线询价

数据
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通用注释

亚单元:

Homodimer; antiparallel disulfide-linked dimer. Heterodimer with PDGFA; antiparallel disulfide-linked dimer. The PDGFB homodimer interacts with PDGFRA and PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB. The heterodimer composed of PDGFA and PDGFB interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts with XLKD1.

功能:

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.

亚细胞位置:

Secreted Released by platelets upon wounding.

数据库链接

UniGene:

Mm.144089

SMR:

P31240

STRING:

10090.ENSMUSP00000000500

KEGG:

mmu:18591

Pfam: