Rat Rab21/ Ras-related protein Rab-21 CLIA Kit

货号:

U4720r

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

特异性:

Natural and recombinant rat Ras-related protein Rab-21

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cancer

规格 & 价格:

关注

Rat Rab21 CLIA Kit

邮箱 *

消息 *

Please 登录.

产品说明书

在线询价

数据
文献
序列 / 3D
反馈墙 (0)

通用注释

亚单元:

Interacts with the cytoplasmic tail of integrins ITGA1, ITGA2, ITGA5, ITGA6, ITGA11 and ITGB1; this interaction is dependent upon its GDP/GTP cycle. Interacts with ANKRD27.

功能:

Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (By similarity). Involved in neurite growth (PubMed:19745841).

亚细胞位置:

Endoplasmic reticulum membrane Lipid-anchor Golgi apparatus Trans-Golgi network Golgi apparatus membrane Early endosome membrane Cytoplasmic vesicle membrane Cleavage furrow Colocalizes with ANKRD27 and VAMP7 in neurites (PubMed:19745841). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (By similarity). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (By similarity).

数据库链接

UniGene:

Rn.162952

SMR:

Q6AXT5

STRING:

10116.ENSRNOP00000005258

KEGG:

rno:299799

Pfam:

PF00071

Uniprot: