Rat Rab26/ Ras-related protein Rab-26 CLIA Kit

货号:

U5176r

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

特异性:

Natural and recombinant rat Ras-related protein Rab-26

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Rat Rab26 CLIA Kit

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通用注释

亚单元:

Interacts with ADRA2B. Interacts with RIMS1.

功能:

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach (By similarity). Plays a role in the secretion of amylase from acinar granules in the parotid gland.

亚细胞位置:

Cytoplasmic vesicle Secretory vesicle membrane Lipid-anchor Cytoplasmic side Golgi apparatus membrane Lipid-anchor Cytoplasmic side Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location (By similarity). Localized immediately around secretory granules in the acinar cells of the parotid gland (PubMed:10857477). Not localized in plasma membranes (PubMed:10857477).

数据库链接

UniGene:

Rn.10975

SMR:

P51156

STRING:

10116.ENSRNOP00000004249

KEGG:

rno:171111

Pfam:

PF00071

Uniprot: