Rat Rab11b/ Ras-related protein Rab-11B CLIA Kit

货号:

U5606r

商标:

EIAab^®

监管等级:

RUO

检测方法:

CLIA

特异性:

Natural and recombinant rat Ras-related protein Rab-11B

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Rat Rab11b CLIA Kit

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通用注释

亚单元:

Interacts with KCNMA1 (By similarity). Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. May interact with TBC1D14. Interacts with ATP6V1E1. Interacts with PI4KB.

功能:

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.

亚细胞位置:

Recycling endosome membrane Lipid-anchor Cytoplasmic side Cytoplasmic vesicle Secretory vesicle Synaptic vesicle membrane Lipid-anchor Cytoplasmic side Cytoplasmic vesicle Phagosome membrane Lipid-anchor Cytoplasmic side Recruited to phagosomes containing S.aureus.

数据库链接

UniGene:

Rn.124832

SMR:

O35509

STRING:

10116.ENSRNOP00000010197

KEGG:

rno:79434

Pfam:

PF00071

Uniprot:

O35509