Rnls (基因名), Renalase (蛋白名), rnls_rat.
产品名称:
Rat Rnls/ Renalase CLIA Kit
肾胺酶
货号:
U1103r
商标:
EIAab®
监管等级:
别名:
Monoamine oxidase-C, alpha-NAD(P)H oxidase/anomerase, MAO-C
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
0.39-25ng/mL
特异性:
Natural and recombinant rat Renalase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Cell Biology
通用注释
亚单元:
N/A
功能:
Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+) (By similarity). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
亚细胞位置:
Secreted
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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