Mouse S1pr5/ Sphingosine 1-phosphate receptor 5 CLIA Kit
鞘氨醇激酶受体5

货号:

U0328m

商标:

EIAab^®

监管等级:

RUO

别名:

Endothelial differentiation G-protein-coupled receptor 8, Lysophospholipid receptor B4, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8, S1P receptor 5, Edg8, Lpb4

检测方法:

CLIA

特异性:

Natural and recombinant mouse Sphingosine 1-phosphate receptor 5

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Mouse S1pr5 CLIA Kit

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通用注释

亚单元:

N/A

功能:

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). S1P activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival. S1P activation on O4-positive pre-oligodendrocytes induces process retraction via a Rho kinase/collapsin response-mediated protein signaling pathway. The S1P-induced survival of mature oligodendrocytes is mediated through a pertussis toxin-sensitive, Akt-dependent pathway. S1P activation on oligodendroglial cells modulates two distinct functional pathways mediating either process retraction or cell survival. These effects depend on the developmental stage of the cell.

亚细胞位置:

Cell membrane Multi-pass membrane protein

数据库链接

UniGene:

Mm.190619

SMR:

Q91X56

STRING:

10090.ENSMUSP00000113843

KEGG:

mmu:94226

Pfam: