Mouse Uba2/ SUMO-activating enzyme subunit 2 CLIA Kit
sumo激活酶亚基2

货号:

U12405m

商标:

EIAab^®

监管等级:

RUO

别名:

Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, Sae2, Uble1b

检测方法:

CLIA

特异性:

Natural and recombinant mouse SUMO-activating enzyme subunit 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Mouse Uba2 CLIA Kit

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通用注释

亚单元:

Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.

功能:

The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

亚细胞位置:

Cytoplasm Nucleus Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention.

数据库链接

UniGene:

Mm.27560

SMR:

Q9Z1F9

STRING:

10090.ENSMUSP00000099807

KEGG:

mmu:50995

Pfam: