AANAT (基因名), Serotonin N-acetyltransferase (蛋白名), snat_human.
产品名称:
Human AANAT/ Serotonin N-acetyltransferase CLIA Kit
5-羟色胺-N-乙酰基转移
货号:
U1937h
商标:
EIAab®
监管等级:
别名:
Aralkylamine N-acetyltransferase, AA-NAT, Serotonin acetylase, SNAT
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
19.5-1250pg/mL
特异性:
Natural and recombinant human Serotonin N-acetyltransferase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Neurosciences
通用注释
亚单元:
Monomer (By similarity). Interacts with several 14-3-3 proteins, including YWHAB, YWHAE, YWHAG and YWHAZ, preferentially when phosphorylated at Thr-31. Phosphorylation on Ser-205 also allows binding to YWHAZ, but with lower affinity. The interaction with YWHAZ considerably increases affinity for arylalkylamines and acetyl-CoA and protects the enzyme from dephosphorylation and proteasomal degradation (By similarity). It may also prevent thiol-dependent inactivation.
功能:
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
亚细胞位置:
Cytoplasm
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