Taf1b (基因名), TATA box-binding protein-associated factor RNA polymerase I subunit B (蛋白名), taf1b_rat.
产品名称:
Rat Taf1b/ TATA box-binding protein-associated factor RNA polymerase I subunit B CLIA Kit
货号:
U3422r
商标:
EIAab®
监管等级:
别名:
RNA polymerase I-specific TBP-associated factor 63 kDa, TATA box-binding protein-associated factor 1B, Transcription initiation factor SL1/TIF-IB subunit B, TAFI63, TBP-associated factor 1B
检测方法:
CLIA
特异性:
Natural and recombinant rat TATA box-binding protein-associated factor RNA polymerase I subunit B
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with FLNA (via N-terminus) (By similarity). Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1C. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits. Interacts with TBP and RRN3.
功能:
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
亚细胞位置:
Nucleus
Nucleolus
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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