Mouse U2af1/ Splicing factor U2AF 35 kDa subunit CLIA Kit

货号:

U3042m

商标:

EIAab^®

监管等级:

RUO

别名:

U2 auxiliary factor 35 kDa subunit, U2 snRNP auxiliary factor small subunit

检测方法:

CLIA

特异性:

Natural and recombinant mouse Splicing factor U2AF 35 kDa subunit

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Epigenetics

规格 & 价格:

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Mouse U2af1 CLIA Kit

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通用注释

亚单元:

Identified in the spliceosome C complex. Heterodimer with U2AF2. Interacts with ZRANB2 (By similarity). Interacts (via RS domain) with PHF5A (via N-terminus).

功能:

Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.

亚细胞位置:

Nucleus Nucleus speckle

数据库链接

UniGene:

Mm.379289

SMR:

Q9D883

STRING:

10090.ENSMUSP00000014684

KEGG:

mmu:108121

Pfam: