UBE2D2 (基因名), Ubiquitin-conjugating enzyme E2 D2 (蛋白名), ub2d2_pig.
产品名称:
Pig UBE2D2/ Ubiquitin-conjugating enzyme E2 D2 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
(E3-independent) E2 ubiquitin-conjugating enzyme D2, E2 ubiquitin-conjugating enzyme D2, Ubiquitin carrier protein D2, Ubiquitin-protein ligase D2, UBC4, UBCH4, UBCH5B
检测方法:
CLIA
特异性:
Natural and recombinant pig Ubiquitin-conjugating enzyme E2 D2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
-
通用注释
亚单元:
Interacts with SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex. Interacts with CNOT4 (via RING domain). Interacts with E3 ubiquitin-protein ligases CBLC, PJA1 and PJA2. Interacts with PDZRN3.
功能:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
亚细胞位置:
N/A
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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