UBIAD1 (基因名), UbiA prenyltransferase domain-containing protein 1 (蛋白名), ubia1_chick.
产品名称:
Chicken UBIAD1/ UbiA prenyltransferase domain-containing protein 1 CLIA Kit
货号:
-
商标:
EIAab®
监管等级:
别名:
RCJMB04_9f15
检测方法:
CLIA
特异性:
Natural and recombinant chicken UbiA prenyltransferase domain-containing protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosyntetic enzyme: coenzyme Q10, also named ubiquinone, plays a important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress.
亚细胞位置:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Golgi apparatus membrane
Multi-pass membrane protein
Mitochondrion
数据库链接
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