USP10 (基因名), Ubiquitin carboxyl-terminal hydrolase 10 (蛋白名), ubp10_chick.
产品名称:
Chicken USP10/ Ubiquitin carboxyl-terminal hydrolase 10 CLIA Kit
货号:
U16169c
商标:
EIAab®
监管等级:
别名:
Deubiquitinating enzyme 10, Ubiquitin thioesterase 10, Ubiquitin-specific-processing protease 10, RCJMB04_16o18
检测方法:
CLIA
特异性:
Natural and recombinant chicken Ubiquitin carboxyl-terminal hydrolase 10
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Epigenetics
通用注释
亚单元:
N/A
功能:
Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteracts MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Component of a regulatory loop that controls autophagy and p53/TP53 levels.
亚细胞位置:
Cytoplasm
Nucleus
数据库链接
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