UBR1 (基因名), E3 ubiquitin-protein ligase UBR1 (蛋白名), ubr1_human.
产品名称:
Human UBR1/ E3 ubiquitin-protein ligase UBR1 CLIA Kit
泛素蛋白连接酶E3成分N识别蛋白1
货号:
U2362h
商标:
EIAab®
监管等级:
别名:
N-recognin-1, RING-type E3 ubiquitin transferase UBR1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I
检测方法:
CLIA
特异性:
Natural and recombinant human E3 ubiquitin-protein ligase UBR1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with RECQL4.
功能:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
亚细胞位置:
Cytoplasm
Cytosol
数据库链接
UniGene:
SMR:
STRING:
KEGG:
MIM:
Pfam:
Uniprot:
验证序列:
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