UCP1 (基因名), Mitochondrial brown fat uncoupling protein 1 (蛋白名), ucp1_bovin.
产品名称:
Bovine UCP1/ Mitochondrial brown fat uncoupling protein 1 CLIA Kit
线粒体的褐色脂肪组织解偶联蛋白1
货号:
U2067b
商标:
EIAab®
监管等级:
别名:
Solute carrier family 25 member 7, Thermogenin, UCP 1, SLC25A7, UCP
检测方法:
CLIA
特异性:
Natural and recombinant bovine Mitochondrial brown fat uncoupling protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cardiovascular
通用注释
亚单元:
Most probably functions as a monomer. Binds one purine nucleotide per monomer. However, has also been suggested to function as a homodimer or a homotetramer. Tightly associates with cardiolipin in the mitochondrion inner membrane; may stabilize and regulate its activity.
功能:
Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.
亚细胞位置:
Mitochondrion inner membrane
Multi-pass membrane protein
数据库链接
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